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  • Introduction The Yoga My Heart Study was a single center

    2019-05-15

    Introduction The Yoga My Heart Study was a single center study that brought to light the therapeutic impact a noninvasive, medication-free intervention has on a costly disease. Atrial fibrillation (AF) is a common cardiac arrhythmia that affects two to three million people worldwide. It is associated with significant morbidity and is also an independent risk factor for mortality. One of the most debilitating complications of the disease is thromboembolic stroke, though it is also known to precipitate and worsen the outcomes of congestive Cyanine3.5 alkyne failure, a disease already known to represent a significant financial burden [1]. The treatment of AF and its associated complications increases healthcare resource utilization and contributes to increasing costs of healthcare, particularly costs associated with hospitalization (Fig. 1).
    Discussion Current AF treatment mainly consists of antiarrhythmic drugs (AADs) and/or catheter ablation. Unfortunately, both strategies have met with less than optimal results and patient satisfaction. While catheter ablation may offer up to 70% of patient׳s freedom from AF, this is at the toll of an invasive procedure. Furthermore, freedom from AF is often defined on the basis of symptom reduction rather than continuous monitoring for true freedom from arrhythmia [3]. While new, promising strategies such as FIRM and ganglionatedplexi ablation are on the, they are still associated with procedure-related risks including cardiac perforation, valvular injury, esophageal-atrial fistula formation, and phrenic nerve injury [4–6]. In addition, many patients who suffer from AF have significant comorbidities that preclude invasive strategies and effective AADs and may require an alternative treatment strategy [7]. In the study conducted by Lakkireddy et al., the authors tested the hypothesis that yoga could reduce the burden and symptoms of AF. This was a small, single center trial that ultimately included 49 participants. The unique approach of this study involved patients serving as their own controls; for the first 3 months, patients continued standard AF AAD therapy, followed by 3 months of 60-min biweekly yoga sessions. Patients were also encouraged to practice yoga at home on a daily basis. The primary outcome was a composite of the reductions in symptomatic AF, symptomatic non-AF, and asymptomatic AF episodes as recorded by a diary and correlated with a non-looping event monitor. Strikingly, the results validate the ability of yoga practice to reduce patient-reported AF symptoms. It also demonstrated a statistically significant impact on quality of life (QoL), mental health, physical functioning, depression, and anxiety. Yoga training reduced symptomatic AF episodes (3.8±3 vs. 2.1±2.6, p<0.001), symptomatic non-AF episodes (2.9±3.4 vs. 1.4±2.0; p<0.001), asymptomatic AF episodes (0.12±0.44 vs. 0.04±0.20; p<0.001), and depression and anxiety (p<0.001) while improving, QoL parameters including physical functioning, general health, vitality, social functioning, and mental health as assessed using the SF-36 (p=0.017, p<0.001, p<0.001, p=0.019, and p<0.001, respectively). There were significant decreases in heart rate and systolic and diastolic blood pressure after yoga training (p<0.001) [2]. Arguably as importantly, there was an objective reduction in AF burden. This is an important finding as many other studies of AF interventions rely solely on subjective history and intermittent EKGs. Furthermore, the study demonstrated a nonpharmacological approach to improve overall QoL in patients with a common medical condition [2]. This may directly result in decreased hospitalization and healthcare costs. Yoga is also an intervention free from medication-related side effects or the complications observed with cardiac ablation. Although the study does not present yoga as a treatment for AF, it does show it to be a favorable adjunct to current therapies.
    Conclusion
    Disclosures
    Conflict of interest